ULK1-IN-3
ULK1-IN-3 (Compound 8) is a novel chromone-based as a potential inhibitor of ULK1. ULK1-IN-3 inhibits cell cycle, autophagy and induces apoptosis, oxidative stress in colon cancer cell lines[1].
Product Specifications
UNSPSC
12352005
Target
Akt; AMPK; Apoptosis; Autophagy; NF-κB; PARP; Reactive Oxygen Species (ROS) ; ULK
Type
Reference compound
Related Pathways
Apoptosis; Autophagy; Cell Cycle/DNA Damage; Epigenetics; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; PI3K/Akt/mTOR
Applications
COVID-19-anti-virus
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ulk1-in-3.html
Smiles
COC1=CC=C(C(C(C2=CC=C(CCl)C=C2)=C(C3=CC=C(OC)C(OC)=C3)O4)=O)C4=C1
Molecular Formula
C25H21ClO5
Molecular Weight
436.88
References & Citations
[1]Shamsudin NF, et al. A novel chromone-based as a potential inhibitor of ULK1 that modulates autophagy and induces apoptosis in colon cancer. Future Med Chem. 2024 Jul 1:1-19.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
ULK1
Frequently Asked Questions
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