GSK-364735
GSK-364735 is a potent antiretroviral agent against human immunodeficiency virus type 1 (HIV-1) and serves as an integrase inhibitor with an IC50 of 8 ± 2 nM. GSK-364735 can be utilized in antiviral research[1].
Product Specifications
CAS Number
[863434-13-3]
Product Name Alternative
S/GSK-364735
UNSPSC
12352005
Target
HIV; HIV Integrase
Type
Reference compound
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/gsk-364735.html
Smiles
O=C(C1=C(O)C2=NC=C(CC3=CC=C(F)C=C3)C=C2N(C)C1=O)NCCO
Molecular Formula
C19H18FN3O4
Molecular Weight
371.36
References & Citations
[1]Garvey EP, et al. The naphthyridinone GSK364735 is a novel, potent human immunodeficiency virus type 1 integrase inhibitor and antiretroviral. Antimicrob Agents Chemother. 2008 Mar;52 (3) :901-8.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2
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