GSK-364735

GSK-364735 is a potent antiretroviral agent against human immunodeficiency virus type 1 (HIV-1) and serves as an integrase inhibitor with an IC50 of 8 ± 2 nM. GSK-364735 can be utilized in antiviral research[1].

Product Specifications

CAS Number

[863434-13-3]

Product Name Alternative

S/GSK-364735

UNSPSC

12352005

Target

HIV; HIV Integrase

Type

Reference compound

Related Pathways

Anti-infection; Metabolic Enzyme/Protease

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/gsk-364735.html

Smiles

O=C(C1=C(O)C2=NC=C(CC3=CC=C(F)C=C3)C=C2N(C)C1=O)NCCO

Molecular Formula

C19H18FN3O4

Molecular Weight

371.36

References & Citations

[1]Garvey EP, et al. The naphthyridinone GSK364735 is a novel, potent human immunodeficiency virus type 1 integrase inhibitor and antiretroviral. Antimicrob Agents Chemother. 2008 Mar;52 (3) :901-8.