Salvinolone
Salvinolone is active against methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococcus (VRE) . Salvinolone shows cytotoxic activity with an IC50 of 47.6 μM against the HL-60 tumor cell line for 72 h[1][2].
Product Specifications
CAS Number
[120278-22-0]
UNSPSC
12352005
Target
Bacterial
Type
Natural Products
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/salvinolone.html
Purity
98.51
Solubility
10 mM in DMSO
Smiles
CC(C(C=C12)=C(O)C(O)=C2[C@@](C)(CCCC3(C)C)C3=CC1=O)C
Molecular Formula
C20H26O3
Molecular Weight
314.42
References & Citations
[1]Mingfeng Xu, et al. Bioactive diterpenes from Clerodendrum kaichianum. Nat Prod Commun. 2011 Jan;6 (1) :3-5.|[2]EnriqueAlvarez-Manzaneda, et al. First synthesis of picealactone C. A new route toward taxodione-related terpenoids from abietic acid. Tetrahedron Letters, Volume 48, Issue 6, 5 February 2007, Pages 989-992.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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