Salvinolone

Salvinolone is active against methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococcus (VRE) . Salvinolone shows cytotoxic activity with an IC50 of 47.6 μM against the HL-60 tumor cell line for 72 h[1][2].

Product Specifications

CAS Number

[120278-22-0]

UNSPSC

12352005

Target

Bacterial

Type

Natural Products

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/salvinolone.html

Purity

98.51

Solubility

10 mM in DMSO

Smiles

CC(C(C=C12)=C(O)C(O)=C2[C@@](C)(CCCC3(C)C)C3=CC1=O)C

Molecular Formula

C20H26O3

Molecular Weight

314.42

References & Citations

[1]Mingfeng Xu, et al. Bioactive diterpenes from Clerodendrum kaichianum. Nat Prod Commun. 2011 Jan;6 (1) :3-5.|[2]EnriqueAlvarez-Manzaneda, et al. First synthesis of picealactone C. A new route toward taxodione-related terpenoids from abietic acid. Tetrahedron Letters, Volume 48, Issue 6, 5 February 2007, Pages 989-992.