DJ-1-IN-1

DJ-1-IN-1 (compound 797780-71-3) is a DJ-1 inhibitor. DJ-1-IN-1 exhibits antiproliferative activity in ACHN cells with an IC50 value of 12.18 μM and can inhibit the Wnt signaling pathway. DJ-1-IN-1 can be used in cancer research[1].

Product Specifications

CAS Number

[797780-71-3]

UNSPSC

12352005

Target

Wnt

Type

Reference compound

Related Pathways

Stem Cell/Wnt

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/dj-1-in-1.html

Purity

98.60

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

ClC1=C(OCCN2C3=CC=CC=C3C(C2=O)=O)C=CC=C1

Molecular Formula

C16H12ClNO3

Molecular Weight

301.72

References & Citations

[1]Ma Y, et al. Discovery of novel covalent inhibitors of DJ-1 through hybrid virtual screening. Future Med Chem. 2024 Apr;16 (7) :665-677.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

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