DJ-1-IN-1
DJ-1-IN-1 (compound 797780-71-3) is a DJ-1 inhibitor. DJ-1-IN-1 exhibits antiproliferative activity in ACHN cells with an IC50 value of 12.18 μM and can inhibit the Wnt signaling pathway. DJ-1-IN-1 can be used in cancer research[1].
Product Specifications
CAS Number
[797780-71-3]
UNSPSC
12352005
Target
Wnt
Type
Reference compound
Related Pathways
Stem Cell/Wnt
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/dj-1-in-1.html
Purity
98.60
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
ClC1=C(OCCN2C3=CC=CC=C3C(C2=O)=O)C=CC=C1
Molecular Formula
C16H12ClNO3
Molecular Weight
301.72
References & Citations
[1]Ma Y, et al. Discovery of novel covalent inhibitors of DJ-1 through hybrid virtual screening. Future Med Chem. 2024 Apr;16 (7) :665-677.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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