Isoprothiolane

Isoprothiolane is a blast fungicide with antifungal, anti-inflammatory and insecticidal activities. Isoprothiolane primarily acts on fungi during the penetration and growth stages of infecting hyphae. Isoprothiolane can be used as an insecticide, pesticide, etc. In addition, Isoprothiolane can reduce serum phospholipid and total lipid concentrations, regulating lipid metabolism. Isoprothiolane is also used in the research of fatty liver[1][2][3][4].

Product Specifications

CAS Number

[50512-35-1]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Fungal; Interleukin Related; Parasite

Type

Reference compound

Related Pathways

Anti-infection; Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Infection; Metabolic Disease; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/isoprothiolane.html

Purity

99.91

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(OC(C)C)/C(C(OC(C)C)=O)=C1SCCS\1

Molecular Formula

C12H18O4S2

Molecular Weight

290.40

Precautions

H302, H315, H319, H335

References & Citations

[1]Matazaemon Uchida, et al. Effect of a Rice Blast Controlling Agent, Isoprothiolane, on Nilaparvata Lugens Stal with Different Levels of Susceptibility to Diazinon. Pest Resistance to Pesticides pp 421-428|[2]Okada H, et al. Effects of isoprothiolane on cell growth of cultured bovine mammary epithelial cells. J Vet Med Sci. 1999 May;61 (5) :553-6.|[3]Kazuo K, et al . Effect of isoprothiolane on fatty acid synthesis. Journal of Pesticide Science, 1979, 4 (3) : 305-313.|[4]Tsuda T, et al. Acute toxicity, accumulation, and excretion of benthiocarb and its degradation products in killifish. Bull Environ Contam Toxicol. 1997 Apr;58 (4) :603-10.