Dupilumab Antibody
Dupilumab (REGN-668) is a fully human monoclonal antibody targeting the IL-4 receptor alpha subunit, thereby blocking IL-4 and IL-13 signaling. It is widely used in research models of atopic dermatitis and other type 2 inflammatory diseases to investigate therapeutic mechanisms in both in vitro and in vivo settings.
Product Specifications
Product Name Alternative
REGN668, REGN-668, REGN 668, SAR231893, SAR-231893, SAR 231893, Dupilumab, IL Receptor, ILReceptor, IL-4, IL-13
Target
IL Receptor, Interleukin
Conjugation
Unconjugated
Field of Research
Immunology & Inflammation
Purification
3-step chromatographic process
Concentration
152.8 mg/mL
Purity
98% by SEC-HPLC
Form
Liquid, PBS, pH 6.
Molecular Weight
149.8 kDa
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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