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NMT-IN-7

NMT-IN-7 is a N-myristoyl transferase (NMT) inhibitor, with IC50s of 2.1 nM for HsNMT1M, 0.6 nM for SU-DHL-10 cell. NMT-IN-7 can be used as a ADC cytotoxin[1].

Product Specifications

CAS Number

3032302-70-5

UNSPSC

12352203

Target

ADC Payload; N-myristoyltransferase

Type

Reference compound

Related Pathways

Antibody-drug Conjugate/ADC Related; Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/nmt-in-7.html

Purity

98.75

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

FC1=C(F)C(OCCC2=C(C)N(C)N=C2C(C(C)(C)C)O)=C(C3=CN4C(CNC)=CN=C4C=C3)C=C1

Molecular Formula

C27H33F2N5O2

Molecular Weight

497.58

References & Citations

[1]Robin Carr, et al. Antibody drug conjugate comprising nmt inhibitor and its use. Patent. WO2024052684

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

ADC Related

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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