NMT-IN-7
NMT-IN-7 is a N-myristoyl transferase (NMT) inhibitor, with IC50s of 2.1 nM for HsNMT1M, 0.6 nM for SU-DHL-10 cell. NMT-IN-7 can be used as a ADC cytotoxin[1].
Product Specifications
CAS Number
[3032302-70-5]
UNSPSC
12352203
Target
ADC Payload; N-myristoyltransferase
Type
Reference compound
Related Pathways
Antibody-drug Conjugate/ADC Related; Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/nmt-in-7.html
Purity
98.75
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
FC1=C(F)C(OCCC2=C(C)N(C)N=C2C(C(C)(C)C)O)=C(C3=CN4C(CNC)=CN=C4C=C3)C=C1
Molecular Formula
C27H33F2N5O2
Molecular Weight
497.58
References & Citations
[1]Robin Carr, et al. Antibody drug conjugate comprising nmt inhibitor and its use. Patent. WO2024052684
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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