Ubiquitin Human Protein

<strong>Ubiquitin Human Protein</strong>_x000D_ <strong>Catalog number:</strong> B2014126_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 0.5 mg_x000D_ <strong>Molecular Weight or Concentration:</strong> 10.7 kDa_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20°C_x000D_ <strong>Keywords:</strong> Ubiquitin, a globular protein is made of 76 amino acids and has lysine residues on its surface. It has a molecular weight of 8565 Da_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Akutsu M, Dikic I, Bremm A. Ubiquitin chain diversity at a glance J Cell Sci. 2016 Mar 1;129(5):875-80._x000D_ 2: Grumati P, Dikic I. Ubiquitin signaling and autophagy J Biol Chem. 2018 Apr 13;293(15):5404-5413._x000D_ 3: Chen RH, Chen YH, Huang TY. Ubiquitin-mediated regulation of autophagy J Biomed Sci. 2019 Oct 21;26(1):80._x000D_ 4: Deshaies RJ, Joazeiro CA. RING domain E3 ubiquitin ligases Annu Rev Biochem. 2009;78:399-434._x000D_ 5: Bernassola F, Chillemi G, Melino G. HECT-Type E3Ubiquitin Ligases in Cancer Trends Biochem Sci. 2019 Dec;44(12):1057-1075._x000D_ 6: Popovic D, Vucic D, Dikic I. Ubiquitination in disease pathogenesis and treatment Nat Med. 2014 Nov;20(11):1242-53._x000D_ 7: Kane LA, Lazarou M, Fogel AI, Li Y, Yamano K, Sarraf SA, Banerjee S, Youle RJ. PINK1 phosphorylates ubiquitin to activate Parkin E3 ubiquitin ligase activity J Cell Biol. 2014 Apr 28;205(2):143-53._x000D_ 8: Leestemaker Y, Ovaa H. Tools to investigate the ubiquitin proteasome system Drug Discov Today Technol. 2017 Dec;26:25-31._x000D_ 9: Gan J, Qiao N, Strahan R, Zhu C, Liu L, Verma SC, Wei F, Cai Q. Manipulation of ubiquitin/SUMO pathways in human herpesviruses infection Rev Med Virol. 2016 Nov;26(6):435-445._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/29334375">10: Hyer ML, Milhollen MA, Ciavarri J, Fleming P, Traore T, Sappal D, Huck J, Shi J, Gavin J, Brownell J, Yang Y, Stringer B, Griffin R, Bruzzese F, Soucy T, Duffy J, Rabino C, Riceberg J, Hoar K, Lublinsky A, Menon S, Sintchak M, Bump N, Pulukuri SM, Langston S, Tirrell S, Kuranda M, Veiby P, Newcomb J, Li P, Wu JT, Powe J, Dick LR, Greenspan P, Galvin K, Manfredi M, Claiborne C, Amidon BS, Bence NF. A small-molecule inhibitor of the ubiquitin activating enzyme for cancer treatment Nat Med. 2018 Feb;24(2):186-193. </a>_x000D_ _x000D_ <strong>Products Related to Ubiquitin Human Protein can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>