Galnon (TFA)
Product Specifications
UNSPSC Description
Galnon TFA is a selective and non-peptide agonist of galanin GAL1 and GAL2 receptor, with Kis of 11.7 and 34.1 μM respectively. Galnon TFA exhibits anticonvulsant and anxiolytic effects[1][2].
Target Antigen
Neuropeptide Y Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein;Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/galnon-tfa.html
Purity
99.15
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
OC(C(F)(F)F)=O.CC(C1=CC=C(C=C1O2)NC([C@H](CCCCN)NC([C@H](CC3CCCCC3)NC(OCC4C5=CC=CC=C5C6=CC=CC=C64)=O)=O)=O)=CC2=O
Molecular Weight
792.84
References & Citations
[1]Bartfai T, et, al. Galmic, a nonpeptide galanin receptor agonist, affects behaviors in seizure, pain, and forced-swim tests. Proc Natl Acad Sci U S A. 2004 Jul 13;101(28):10470-5.|[2]Rajarao SJR, et, al. Anxiolytic-like activity of the non-selective galanin receptor agonist, galnon. Neuropeptides. 2007 Oct;41(5):307-20.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture and light)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-103536A/Galnon-TFA-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-103536A/Galnon-TFA-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
1217448-19-5
Available Sizes
Curated Selection
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