Gefapixant (Standard)
Gefapixant (Standard) is the analytical standard of Gefapixant. This product is intended for research and analytical applications. Gefapixant is an orally active and potent purinergic P2X3 receptor (P2X3R) antagonist, with IC50 values of ~30 nM versus recombinant hP2X3 homotrimers and 100-250 nM at hP2X2/3 heterotrimeric receptors. Gefapixant can be used for the research of chronic cough and knee osteoarthritis[1][2][3].
Product Specifications
CAS Number
1015787-98-0
Product Name Alternative
MK-7264 (Standard) ; AF-219 (Standard)
UNSPSC
12352005
Target
P2X Receptor; Reference Standards
Type
Reference Standards
Related Pathways
Membrane Transporter/Ion Channel; Others
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/gefapixant-standard.html
Smiles
O=S(C1=CC(OC2=CN=C(N)N=C2N)=C(C(C)C)C=C1OC)(N)=O
Molecular Formula
C14H19N5O4S
Molecular Weight
353.40
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
