Z-VEID-FMK
Z-VEID-FMK (Z-VE (OMe) ID (OMe) -FMK) is a selective and irreversible caspase-6 peptide inhibitor. Z-VEID-FMK alleviates the drug-induced augmentation of caspase-6 activity, DNA fragmentation, and cell apoptosis[1][2].
Product Specifications
CAS Number
210344-96-0
Product Name Alternative
Z-VE (OMe) ID (OMe) -FMK
UNSPSC
12352209
Target
Apoptosis; Caspase
Type
Peptides
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/z-veid-fmk.html
Purity
95.0
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
O=C(OCC1=CC=CC=C1)N[C@@H](C(C)C)C(N[C@@H](CCC(OC)=O)C(N[C@@H]([C@@H](C)CC)C(N[C@H](C(CF)=O)CC(OC)=O)=O)=O)=O
Molecular Formula
C31H45FN4O10
Molecular Weight
652.71
References & Citations
[1]S-T Lee, et al. Apoptotic insults to human HepG2 cells induced by S- (+) -ketamine occurs through activation of a Bax-mitochondria-caspase protease pathway. Br J Anaesth. 2009 Jan;102 (1) :80-9. |[2]Philippe P Monnier, et al. Involvement of caspase-6 and caspase-8 in neuronal apoptosis and the regenerative failure of injured retinal ganglion cells. J Neurosci. 2011 Jul 20;31 (29) :10494-505.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, stored under nitrogen, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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