(±) -H3RESCA-TFP

(±) -H3RESCA-TFP ((±) -H3L28) is a tetrafluorophenyl ester derivative of restrained complexing agent (RESCA) . (±) -H3RESCA-TFP can be used to conjugate the chelator with a biomolecule via amine coupling (e.g., N terminus and/or the ε-amino groups of lysine) [1].

Product Specifications

CAS Number

[1919794-40-3]

Product Name Alternative

(±) -H3L28

UNSPSC

12352005

Target

Drug Derivative

Type

Reference compound

Related Pathways

Others

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/racemic-h3resca-tfp.html

Purity

98.15

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(CC1=CC=C(CN(CC(O)=O)[C@@H]2CCCC[C@H]2N(CC(O)=O)CC(O)=O)C=C1)OC3=C(F)C(F)=CC(F)=C3F

Molecular Formula

C27H28F4N2O8

Molecular Weight

584.51

References & Citations

[1]Cleeren F, et al. Direct fluorine-18 labeling of heat-sensitive biomolecules for positron emission tomography imaging using the Al18F-RESCA method. Nat Protoc. 2018 Oct;13 (10) :2330-2347.