(S) - (+) -Ibuprofen-d3
(S) - (+) -Ibuprofen-d3 is a deuterium labeled (S) - (+) -Ibuprofen. (S) - (+) -Ibuprofen is the S (+) -enantiomer of Ibuprofen that inhibits COX-1 and COX-2 activity with IC50s of 2.1 μM and 1.6 μM. (S) - (+) -Ibuprofen has analgesic, antiinflammatory and antipyretic effects[1][2].
Product Specifications
CAS Number
1329643-44-8
Product Name Alternative
(S) -Ibuprofen D3
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
COX
Type
Isotope-Labeled Compounds
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Purity
99.96
Solubility
10 mM in DMSO|DMSO : 100mg/mL (ultrasonic) |Ethanol : 100mg/mL (ultrasonic)
Smiles
OC([C@H](C1=CC=C(CC(C)C)C=C1)C([2H])([2H])[2H])=O
Molecular Formula
C13H15D3O2
Molecular Weight
209.30
Precautions
H302, H315, H319, H335
References & Citations
[1]Evans AM, et al. Comparative pharmacology of S (+) -ibuprofen and (RS) -ibuprofen. Clin Rheumatol. 2001 Nov;20 Suppl 1:S9-14.|[2]Xu HR, et al. The effect of CYP2C19 activity on pharmacokinetics of lansoprazole and its active metabolites in healthy subjects. Pharm Biol. 2010 Aug;48 (8) :947-52.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Isoform
COX-1; COX-2
Available Sizes
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