(S) - (+) -Ibuprofen-d3

(S) - (+) -Ibuprofen-d3 is a deuterium labeled (S) - (+) -Ibuprofen. (S) - (+) -Ibuprofen is the S (+) -enantiomer of Ibuprofen that inhibits COX-1 and COX-2 activity with IC50s of 2.1 μM and 1.6 μM. (S) - (+) -Ibuprofen has analgesic, antiinflammatory and antipyretic effects[1][2].

Product Specifications

CAS Number

[1329643-44-8]

Product Name Alternative

(S) -Ibuprofen D3

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

COX

Type

Isotope-Labeled Compounds

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Purity

99.96

Solubility

10 mM in DMSO|DMSO : 100mg/mL (ultrasonic) |Ethanol : 100mg/mL (ultrasonic)

Smiles

OC([C@H](C1=CC=C(CC(C)C)C=C1)C([2H])([2H])[2H])=O

Molecular Formula

C13H15D3O2

Molecular Weight

209.30

Precautions

H302, H315, H319, H335

References & Citations

[1]Evans AM, et al. Comparative pharmacology of S (+) -ibuprofen and (RS) -ibuprofen. Clin Rheumatol. 2001 Nov;20 Suppl 1:S9-14.|[2]Xu HR, et al. The effect of CYP2C19 activity on pharmacokinetics of lansoprazole and its active metabolites in healthy subjects. Pharm Biol. 2010 Aug;48 (8) :947-52.