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Ambruticin

Product Specifications

CAS Number

58857-02-6

UNSPSC Description

Ambruticin (W7783) is an orally active and potent antifungal antibiotic. Ambruticin represents a class of antibiotics, that can be isolated from a strain of Polyangium cellulosum var. fulvum, a bacterium belonging to the class Myxobacteriales. Ambruticin is a cyclopropyl-polyene-pyran acid and is active against fungi[1].

Target Antigen

Antibiotic; Fungal

Type

Natural Products

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/ambruticin.html

Solubility

10 mM in DMSO

Smiles

OC(C[C@H](C[C@@H]([C@H]1O)O)O[C@H]1/C=C/[C@@H]2[C@H]([C@H]2C)/C=C/[C@@H](C)/C=C([C@@H]3O[C@@H](C(C)=CC3)CC)\C)=O

Molecular Weight

474.63

References & Citations

[1]Ringel SM, et al. Ambruticin (W7783), a new antifungal antibiotic. J Antibiot (Tokyo). 1977 May;30(5):371-5.|[2]Ringel SM. In vitro and in vivo studies of ambruticin (W7783): new class of antifungal antibiotics. Antimicrob Agents Chemother. 1978 May;13(5):762-9.

Shipping Conditions

Room temperature

Clinical Information

No Development Reported

Frequently Asked Questions

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