20-Hydroxylucidenic acid E2

20-Hydroxylucidenic acid E2 is a triterpenoid compound found in Ganoderma lucidum. It exhibits significant inhibitory effects on inflammation induced by TPA (HY-18739) . Additionally, 20-Hydroxylucidenic acid E2 can suppress the expression of EBV early antigen induced by TPA (HY-18739), with a IC50 of 290 mol ratio/32 pmol TPA (meaning that when the molar concentration of this compound is 290 times that of 32 pmol of TPA, it can inhibit 50% of EBV early antigen expression) . Therefore, 20-Hydroxylucidenic acid E2 has potential applications in anti-inflammatory and anticancer research[1].

Product Specifications

CAS Number

[852567-75-0]

UNSPSC

12352211

Target

EBV

Type

Reference compound

Related Pathways

Anti-infection

Field of Research

Cancer; Infection

Assay Protocol

https://www.medchemexpress.com/20-hydroxylucidenic-acid-e2.html

Smiles

C[C@@]12[C@]([C@@H](C(C3=C1C(C[C@]4([H])[C@@]3(CC[C@@H](C4(C)C)O)C)=O)=O)OC(C)=O)([C@H](CC2=O)C(C)(O)CCC(O)=O)C

Molecular Formula

C29H40O9

Molecular Weight

532.62

References & Citations

[1]Akihisa T, et al. Oxygenated lanostane-type triterpenoids from the fungus Ganoderma l ucidum[J]. Journal of Natural Products, 2005, 68 (4) : 559-563.