Anti-GLUT10 Antibody

Rabbit Polyclonal Antibody specific to GLUT10

Product Specifications

CAS Number

9007-83-4

Product Name Alternative

Glucose transporter type 10, GLUT-10

Gene Name

SLC2A10

NCBI Gene ID

UniProt

O95528

Cellular Locus

Endomembrane system, Cytoplasm, perinuclear region

Host

Rabbit

Reactivity

Human

Immunogen

Synthetic peptide corresponding to amino acids 367-385 (ILSTAKKTKPHPRSGDPSA) of human GLUT10 conjugated to KLH at the N- terminus.

Target Antigen

Solute carrier family 2, facilitated glucose transporter member 10

Target

GLUT10

Clonality

Polyclonal

Type

Antibody

Applications

Field of Research

Neuroscience

Purification Method

Purified by peptide immuno-affinity chromatography

Concentration

Lot Specific

Dilution

Dilute in PBS or medium that is identical to that used in the assay system.

Format

Purified

Form

Liquid

Buffer

Phosphate Buffered Saline

Function

Facilitative glucose transporter required for the development of the cardiovascular system. {PubMed:11592815, PubMed:16550171}.

Additionnal Information

Immunoblotting: use at 1:500 dilution. A band of approximately 57 kDa is detected. <br><br>Positive control: transfected cell lysate

Storage Conditions

This antibody is stable for at least one (1) year at -20°C. Avoid multiple freeze- thaw cycles.

Specificity

This antibody recognizes human GLUT10.

Formulation

PBS, pH 7.4.

Buffer pH

pH 7.4

Target Background

Non-insulin-dependent diabetes mellitus (NIDDM) is a multifactoral disease with both environmental and genetic causes. Genome-wide screening has identified several susceptibility loci for NIDDM within the human genome. Most mammalian cells transport glucose through a family of membrane proteins known as glucose transporters (GLUT or SLC2A family). The gene for GLUT10, localized to human chromosome 20q12-q13.1, is a candidate gene for NIDDM susceptibility. It is widely expressed, with highest levels in liver and pancreas.