IBRD4-BD1 (diTFA)
IBRD4-BD1 diTFA is selective BRD4 bromodomain inhibitor. iBRD4-BD1 diTFA has inhibition activity for BRD4 bromodomain with an IC50 value of 12 nM. iBRD4-BD1 diTFA can be used for the research of inflammation and oncology[1].
Product Specifications
CAS Number
[2839318-20-4]
UNSPSC
12352005
Target
Epigenetic Reader Domain
Type
Reference compound
Related Pathways
Epigenetics
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/ibrd4-bd1-ditfa.html
Purity
99.52
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
FC(F)(C1=CC=C(C2=C(C3=CC=NC(OC4=CC(C(C)C)=CC=C4C)=N3)N(C5CCNCC5)C=N2)C=C1)F.OC(C(F)(F)F)=O.OC(C(F)(F)F)=O
Molecular Formula
C33H32F9N5O5
Molecular Weight
749.62
References & Citations
[1]Anand Divakaran, et al. Development of an N-Terminal BRD4 Bromodomain-Targeted Degrader. ACS Med Chem Lett. 2022 Sep 29;13 (10) :1621-1627.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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