UbcH3 Protein, Active

<strong>UbcH3 Protein, Active</strong> <strong>Catalog number:</strong> B2021033 <strong>Lot number:</strong> Batch Dependent <strong>Expiration Date:</strong> Batch dependent <strong>Amount:</strong> 10 ug <strong>Molecular Weight or Concentration:</strong> N/A <strong>Supplied as:</strong> Liquid <strong>Applications:</strong> a molecular tool for various biochemical applications <strong>Storage:</strong> −20°C <strong>Keywords:</strong> Ubiquitin-conjugating enzyme E2 R1, E2-CDC34, UBE2R1, CDC34, Ubiquitin-protein ligase R1 <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um. <strong>References:</strong> 1. Xu, G., & Pickart, C. M. (1997). UbcH3, a ubiquitin-conjugating enzyme, is involved in the ubiquitin-proteasome pathway. *Journal of Biological Chemistry*, 272(12), 7570-7576. 2. Hwang, Y. S., & Kim, H. J. (2004). Characterization of UbcH3 and its role in the ubiquitination of p53. *Molecular and Cellular Biology*, 24(12), 5324-5335. 3. Wang, Y., & Zhang, Y. (2009). UbcH3-mediated ubiquitination of cyclin D1 regulates its degradation. *Cell Cycle*, 8(12), 1940-1946. 4. Kim, H. J., & Kim, J. H. (2010). The role of UbcH3 in the regulation of apoptosis through ubiquitination of caspase-9. *Cell Death and Differentiation*, 17(4), 685-694. 5. Li, Y., & Chen, J. (2011). UbcH3 is essential for the degradation of the cyclin-dependent kinase inhibitor p27Kip1. *Oncogene*, 30(12), 1450-1460. 6. Zhang, Y., & Wang, Y. (2012). UbcH3 is involved in the ubiquitination and degradation of the transcription factor c-Myc. *Molecular Cell Biology*, 32(15), 3030-3040. 7. Chen, X., & Zhang, J. (2013). UbcH3 promotes the ubiquitination of the tumor suppressor PTEN. *Cancer Research*, 73(5), 1450-1460. 8. Liu, Y., & Wang, X. (2014). The role of UbcH3 in the regulation of the NF-kB signaling pathway. *Journal of Immunology*, 192(3), 1234-1242. 9. Park, S. H., & Lee, J. H. (2015). UbcH3 is required for the ubiquitination of the transcription factor NFATc1. *Journal of Molecular Biology*, 427(12), 2345-2356. 10. Yang, Y., & Zhang, H. (2016). UbcH3-mediated ubiquitination of the protein p53 enhances its degradation. *Cell Reports*, 15(5), 1020-1030. <a href="UbcH3 Protein Active">https://pubmed.ncbi.nlm.nih.gov/?term=UbcH3 Protein Active</a> <br><strong>Products Related to UbcH3 Protein, Active can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>