Anti-PAX-8 Antibody
Anti-PAX-8 Antibody is in ready-to-use format. PAX-8 belongs to the paired box (PAX) family of transcription factors which play an important role in early development such as with thyroid follicular cells and the expression of thyroid-specific genes; however mutations in the PAX8 gene is found to be associated with thyroid follicular carcinomas. PAX-8 is also found to be expressed in simple ovarian inclusion cysts and non-ciliated mucosal cells of the fallopian tubes. It has been found to be as useful marker for renal epithelial tumors, ovarian cancer and for differential diagnoses in lung and neck tumors. Anti-PAX-8 can be used in conjunction with other markers such as uroplakin, mammaglobin and TTF-1 to determine the primary sites of invasive micropapilary carcinomas of ovary.
Product Specifications
Reactivity
Human
Immunogen
Recombinant Protein
Clonality
Monoclonal
Clone
BKJE260
Conjugation
Unconjugated
Field of Research
Stem Cell & Developmental Biology
Purification
Purified
Purity
Purified
Form
Tris Buffer, pH 7.3 - 7.7, with 1% rAlbumin and <0.1% Sodium Azide
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
1:50-1:200
Tested Applications
ELISA, IHC
Host or Source
Rabbit
Preservative
Tris Buffer, pH 7.3 - 7.7, with 1% rAlbumin and <0.1% Sodium Azide
Isotype
IgG
Frequently Asked Questions
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