Oridonin
Oridonin (NSC-250682), a diterpenoid isolated from Rabdosia rubescens, acts as an inhibitor of AKT, with IC50s of 8.4 and 8.9 μM for AKT1 and AKT2; Oridonin possesses anti-tumor, anti-bacterial and anti-inflammatory effects.
Product Specifications
CAS Number
[28957-04-2]
Product Name Alternative
NSC-250682; Isodonol
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Akt; Bacterial
Type
Natural Products
Related Pathways
Anti-infection; PI3K/Akt/mTOR
Applications
Cancer-Kinase/protease
Field of Research
Cancer; Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/Oridonin.html
Purity
99.89
Solubility
DMSO : 62.5 mg/mL (ultrasonic)
Smiles
O[C@@H]1[C@]2(CO3)[C@@]([C@H](O)[C@]3(O)[C@]45[C@@]2([H])CC[C@](C(C5=O)=C)([H])[C@@]4([H])O)([H])C(C)(C)CC1
Molecular Formula
C20H28O6
Molecular Weight
364.43
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
Phase 4
Isoform
Akt1; Akt2
Available Sizes
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
5- ((2- ((2,3-Dimethyl-2H-indazol-6-yl) (methyl) amino) pyrimidin-4-yl) amino) -2-methylbenzenesulfonamide Hydrochloride
5- ((2- ((2,3-Dimethyl-2H-indazol-6-yl) (methyl) amino) pyrimidin-4-yl) amino) -2-methylbenzenesulfonamide Hydrochloride
MAFG, NT (MAFG, Transcription factor MafG, V-maf musculoaponeurotic fibrosarcoma oncogene homolog G, hMAF) (MaxLight 550) discontinued
