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Anti-OX40 Antibody

OX40 or CD134 is encoded by the TNFRSF4 gene, a member of the TNF-receptor superfamily. Expression of OX40 is found in activated CD4 and CD8 T cells, but is absent in resting naïve T cells and most resting memory T cells. Anti-OX40 Antibody detects the presence of OX40, which plays a major role in proliferation and differentiation of naïve T cells into a population of heterogeneous effector T cells, and has been found to promote proliferation and survival of CD8 T cells. Thus, OX40 and it's ligand, OX40L, is a key player in pathways involving the immune system such as long-term T-cell immunity.

Product Specifications

Reactivity

Human

Immunogen

Recombinant Protein

Clonality

Monoclonal

Clone

BKJE386

Conjugation

Unconjugated

Field of Research

Immunology & Inflammation

Purification

Purified

Purity

Purified

Form

Tris Buffer, pH 7.3 - 7.7, with 1% rAlbumin and <0.1% Sodium Azide

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Applications Notes

1:50-1:200

Tested Applications

ELISA, IHC

Host or Source

Rabbit

Preservative

Tris Buffer, pH 7.3 - 7.7, with 1% rAlbumin and <0.1% Sodium Azide

Isotype

IgG

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