Anti-CDK4 Antibody
CDK4 controls cell growth during the cell cycle G1 phase. It is reported that D-type cyclin upregulates Cdk4 activity, whereas binding to the Cdk inhibitor p16 downregulates Cdk4 activity. Cyclin D-CDK4 complexes integrates various mitogenenic and antimitogenic signals and serves as sensitive and specific for atypical lipomatous tumor / well differentiated liposarcoma or dedifferentiated liposarcoma.
Product Specifications
Reactivity
Human
Immunogen
Recombinant Protein
Clonality
Monoclonal
Clone
BKJE299
Conjugation
Unconjugated
Field of Research
Signal Transduction
Purification
Purified
Purity
Purified
Form
Tris Buffer, pH 7.3 - 7.7, with 1% rAlbumin and <0.1% Sodium Azide
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
1:50-1:200
Tested Applications
ELISA, IHC
Host or Source
Rabbit
Preservative
Tris Buffer, pH 7.3 - 7.7, with 1% rAlbumin and <0.1% Sodium Azide
Isotype
IgG
Frequently Asked Questions
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