Enalapril (maleate)
Enalapril (MK-421) maleate, the active metabolite of enalapril, is an angiotensin-converting enzyme (ACE) inhibitor.
Product Specifications
CAS Number
[76095-16-4]
Product Name Alternative
MK-421 (maleate)
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Angiotensin-converting Enzyme (ACE)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-anti-virus
Field of Research
Cardiovascular Disease; Cancer
Assay Protocol
https://www.medchemexpress.com/enalapril-maleate.html
Purity
99.99
Solubility
DMSO : ≥ 50 mg/mL|H2O : 33.33 mg/mL (ultrasonic; warming)
Smiles
O=C(O)[C@H]1N(C([C@H](C)N[C@H](C(OCC)=O)CCC2=CC=CC=C2)=O)CCC1.O=C(O)/C=C\C(O)=O
Molecular Formula
C24H32N2O9
Molecular Weight
492.52
Precautions
H302, H315, H319, H335
References & Citations
[1]Liu, Y.H., et al., Comparison of captopril and enalapril to study the role of the sulfhydryl-group in improvement of endothelial dysfunction with ACE inhibitors in high dieted methionine mice. J Cardiovasc Pharmacol, 2006. 47 (1) : p. 82-8.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
Launched
Citation 01
BioRxiv. 2024 November 28.|bioRxiv. 2025 Jun 27:2025.06.24.660441.|Cardiooncology. 2025 Nov 13;11 (1) :106.|Environ Pollut. 2019 Apr:247:927-934.|Int J Nanomedicine. 2025 Oct 27:20:12993-13006.|Toxicol Lett. 2019 Jul:309:42-50.|Toxicology. 2023 Mar 1:486:153442.|Am J Transl Res. 2022 Jan 15;14 (1) :211-222.|Elife. 2025 Aug 28:14:RP104774.|Int J Clin Exp Pathol. 2020 May 1;13 (5) :827-836.|Nat Commun. 2023 May 2;14 (1) :2523.|Ren Fail. 2023;45 (2) :2253924.
Available Sizes
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