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PLTX-II

PLTX-II is a calcium channel blocker. PLTX-II has a 44-residue peptide containing ten Cys residues and an O-palmitoylated threonine amide at the carboxy-terminus[1].

Product Specifications

UNSPSC

12352209

Target

Calcium Channel

Type

Peptides

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/pltx-ii.html

Solubility

10 mM in DMSO

Smiles

O=C(N[C@@H](CC(O)=O)C(N[C@@H](CSSC[C@@H](C(N[C@@H](CC(O)=O)C(N[C@@H](CC(O)=O)C(N[C@@H](CSSC[C@@H](C(N[C@@H](CC(O)=O)C(N[C@@H]([C@H](OC(CCCCCCCCCCCCCCC)=O)C)C(N)=O)=O)=O)NC1=O)C(N[C@@H](CC2=CC=C(C=C2)O)C(N[C@H]3[C@H](O)C)=O)=O)=O)=O)=O)NC4=O)C(N[C@@H](CO)C(N[C@@H](C)C(N[C@@H]([C@H](O)C)C(NCC(N[C@@H](CC(O)=O)C(N[C@@H]([C@H](O)C)C(N[C@@H](CSSC[C@@H](C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CSSC[C@@H](C(N[C@H]5CCCNC(N)=N)=O)NC6=O)C(NCC(N[C@@H]([C@H](O)C)C(N7[C@@H](CCC7)C(N[C@@H](CC8=CNC9=CC=CC=C89)C(NCC(N[C@@H](C)C(N[C@H]6CC(N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)NC3=O)C(N[C@@H](CC(O)=O)C(N[C@@H](CC%10=CNC=N%10)C(N[C@@H]([C@H](O)C)C(N[C@@H](CCCCN)C(N[C@@H](CCCCN)C(N[C@H]4CSSC[C@@H](C(N[C@@H](CC(O)=O)C(N[C@@H](CC%11=CC=C(C=C%11)O)C(N[C@@H](CC%12=CC=C(C=C%12)O)C(N[C@@H](CCCCN)C(N[C@@H](C)C(N[C@H]1CCCNC(N)=N)=O)=O)=O)=O)=O)=O)NC5=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](C)N

Molecular Formula

C208H313N61O70S10

Molecular Weight

5108.73

References & Citations

[1]J Bódi, et al. Synthesis of an O-palmitoylated 44-residue peptide amide (PLTX II) blocking presynaptic calcium channels in Drosophila. Pept Res. 1995, 84, 4.

Shipping Conditions

Room temperature

Scientific Category

Peptides

Clinical Information

No Development Reported

Frequently Asked Questions

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