Ramelteon metabolite M-II
Ramelteon metabolite M-II is the major metabolite of Ramelteon, with IC50s of 208 pM, 1470 pM for human melatonin receptors (MT1 or MT2) . Ramelteon is a selective melatonin agonist.
Product Specifications
CAS Number
[896736-21-3]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Drug Metabolite; Melatonin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Metabolic Enzyme/Protease; Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Neurological Disease; Endocrinology
Assay Protocol
https://www.medchemexpress.com/Ramelteon_metabolite_M-II.html
Purity
98.24
Smiles
CC(O)C(NCC[C@@H]1CCC2=CC=C3OCCC3=C12)=O
Molecular Formula
C16H21NO3
Molecular Weight
275.34
Precautions
H302, H315, H319, H335
References & Citations
[1]Nishiyama K, et al. Pharmacological characterization of M-II, the major human metabolite of ramelteon. Pharmacology. 2014;93 (3-4) :197-201.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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