CZL-046
CZL-046 (compund 29) is an oral p300 bromodomain inhibitor[1].
Product Specifications
CAS Number
[3032444-02-0]
UNSPSC
12352005
Target
Epigenetic Reader Domain
Type
Isotope-Labeled Compounds
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
O=C1N([C@@H](C[C@@H]1F)C2=NC3=CC(C4=C(ON=C4C)C)=CC=C3N2[C@H]5CC[C@@H](CC5)OC([2H])([2H])[2H])C6=CC(F)=C(C=C6)F
Molecular Formula
C29H26D3F3N4O3
Molecular Weight
541.58
References & Citations
[1]Chen Z, et al. Discovery of CZL-046 with an (S) -3-Fluoropyrrolidin-2-one Scaffold as a p300 Bromodomain Inhibitor for the Treatment of Multiple Myeloma. J Med Chem. 2024 Oct 24;67 (20) :18606-18628.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
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