Bictegravir (sodium) (Standard)

Bictegravir (sodium) (Standard) is the analytical standard of Bictegravir (sodium) . This product is intended for research and analytical applications. Bictegravir sodium is a potent inhibitor of HIV-1 integrase, with an IC50 of 7.5 nM. Bictegravir sodium exhibits potent and selective anti-HIV activity and low cytotoxicity[1].

Product Specifications

CAS Number

[1807988-02-8]

Product Name Alternative

GS-9883 (sodium) (Standard)

UNSPSC

12352005

Target

HIV; HIV Integrase; Reference Standards

Type

Reference compound

Related Pathways

Anti-infection; Metabolic Enzyme/Protease; Others

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/bictegravir-sodium-standard.html

Purity

99.62

Smiles

O=C1N([C@](CC2)([H])C[C@]2([H])O3)[C@@]3([H])CN(C=C(C(NCC(C(F)=CC(F)=C4)=C4F)=O)C5=O)C1=C5O[Na]

Molecular Formula

C21H17F3N3NaO5

Molecular Weight

471.36

References & Citations

[1]Tsiang M, et al. Antiviral Activity of Bictegravir (GS-9883), a Novel Potent HIV-1 Integrase Strand Transfer Inhibitor with an Improved Resistance Profile. Antimicrob Agents Chemother. 2016 Nov 21;60 (12) :7086-7097.