LolCDE-IN-4
LolCDE-IN-4 (Compound 1) is exhibits antibacterial efficacy against gram negative bacteria Escherichia coli (MIC of 0.25-32 µg/ml) and Haemophilus influenzae, through inhibition LolCDE complex and disruption of lipoproteins release from the inner membrane[1].
Product Specifications
CAS Number
1859918-13-0
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/lolcde-in-4.html
Purity
99.39
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC(C1=NC(C2=CC=NC=C2)=C(C3=CC=C(OCCO4)C4=C3)N1)(C)C
Molecular Formula
C20H21N3O2
Molecular Weight
335.40
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501
References & Citations
[1]McLeod SM, et al., Small-molecule inhibitors of gram-negative lipoprotein trafficking discovered by phenotypic screening. J Bacteriol. 2015 Mar;197 (6) :1075-82.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
LC423344 20 µg
CCBL2 (KYAT3) (NM_001008661) Human Over-expression Lysate
Sign In for Pricing
View Details 
RDR-CD83-Hu-01 96 Tests
Human Cluster Of Differentiation 83 (CD83) ELISA Kit
Sign In for Pricing
View Details RDR-CD83-Hu-02 48 Tests
Human Cluster Of Differentiation 83 (CD83) ELISA Kit
Sign In for Pricing
View Details