Ro 31-1118 (free base)

Ro 31-1118 Free base is a compound exhibiting weak antihypertensive activity in patients with mild hypertension. Ro 31-1118 Free base demonstrated a reduction in heart rates and blood pressure post-exercise at varying doses. Ro 31-1118 Free base exhibited linear pharmacokinetics within the 10-80 mg dose range. Ro 31-1118 Free base showed no significant impact on diastolic blood pressure or adverse effects during the study.

Product Specifications

CAS Number

[81228-35-5]

UNSPSC

12352101

Target

Endogenous Metabolite

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/ro-31-1118-free-base.html

Smiles

FC1=CC=C(CCOCCOC2=CC=C(C=C2)OCC(CNC(C)C)O)C=C1

Molecular Formula

C22H30FNO4

Molecular Weight

391.48

References & Citations

[1]Ro 31-1118, a new cardioselective beta-adrenoceptor antagonist. Pharmacokinetics and effects on heart rate and blood pressure in mild hypertensives