Malachite green (hemioxalate)
Malachite green hemioxalate (MCCK1) is a triphenylmethane dye which can be used to detect the release of phosphate in enzymatic reactions. Malachite green hemioxalate has antibacterial activity, which is attributed to inhibition of intracellular enzymes, insertion into DNA and/or interaction with cell membranes. Malachite green hemioxalate is also a potent and selective inhibitor of IKBKE, and inhibits its downstream targets such as IκBα, p65 and IRF3. Malachite green hemioxalate exhibits antitumor activity in vitro and in vivo[1][2][3].
Product Specifications
CAS Number
2437-29-8
Product Name Alternative
MCCK1
UNSPSC
12171500
Hazard Statement
H301, H318, H361, H410
Target
Apoptosis; Fungal; IKK; NF-κB
Type
Dye Reagents
Related Pathways
Anti-infection; Apoptosis; NF-κB
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/malachite-green-hemioxalate.html
Purity
98.0
Solubility
DMSO : ≥ 10 mg/mL
Smiles
C/[N+](C)=C1C=C/C(C=C/1)=C(C2=CC=C(N(C)C)C=C2)\C3=CC=CC=C3.O=C(O)C([O-])=O.O=C(O)C(O)=O.[1/2]
Molecular Formula
C23H25N2.1/2C2H2O4.C2HO4
Molecular Weight
463.50
Precautions
H301, H318, H361, H410
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Dye Reagents
Clinical Information
No Development Reported
Frequently Asked Questions
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