Casein kinase 1��-IN-15
Casein kinase 1δ-IN-15 is an inhibitor for casein kinase 1 (CK1δ), with an IC50 of 0.045 μM[1].
Product Specifications
CAS Number
[2765264-27-3]
UNSPSC
12352005
Target
Casein Kinase
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Stem Cell/Wnt
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/casein-kinase-1δ-in-15.html
Solubility
10 mM in DMSO
Smiles
CC1(C)N2C(COC1)=C(C3=C4C(NN=C4)=NC=C3)C(C5=NC=C(F)C=C5)=N2
Molecular Formula
C19H17FN6O
Molecular Weight
364.38
References & Citations
[1]Stefan M.C., et al., Structure-Based Optimization of Selective and Brain Penetrant CK1δ Inhibitors for the Treatment of Circadian Disruptions, ACS Med. Chem. Lett., 2024 March.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CK1
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