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Casein kinase 1��-IN-15

Casein kinase 1δ-IN-15 is an inhibitor for casein kinase 1 (CK1δ), with an IC50 of 0.045 μM[1].

Product Specifications

CAS Number

[2765264-27-3]

UNSPSC

12352005

Target

Casein Kinase

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Stem Cell/Wnt

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/casein-kinase-1δ-in-15.html

Solubility

10 mM in DMSO

Smiles

CC1(C)N2C(COC1)=C(C3=C4C(NN=C4)=NC=C3)C(C5=NC=C(F)C=C5)=N2

Molecular Formula

C19H17FN6O

Molecular Weight

364.38

References & Citations

[1]Stefan M.C., et al., Structure-Based Optimization of Selective and Brain Penetrant CK1δ Inhibitors for the Treatment of Circadian Disruptions, ACS Med. Chem. Lett., 2024 March.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

CK1

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