Naproxen (sodium) (Standard)
Product Specifications
UNSPSC Description
Naproxen (sodium) (Standard) is the analytical standard of Naproxen (sodium). This product is intended for research and analytical applications. Naproxen sodium is a COX-1 and COX-2 inhibitor with IC50s of 8.72 and 5.15 μM, respectively in cell assay.
Target Antigen
Autophagy; COX
Type
Reference Standards
Related Pathways
Autophagy;Immunology/Inflammation
Field of Research
Inflammation/Immunology; Cancer
Assay Protocol
https://www.medchemexpress.com/naproxen-sodium-standard.html
Solubility
H2O : 75 mg/mL (ultrasonic;warming)
Smiles
C[C@H](C(O[Na])=O)C1=CC2=CC=C(OC)C=C2C=C1
Molecular Weight
252.24
References & Citations
[1]Mitchell JA, et al. Selectivity of nonsteroidal antiinflammatory drugs as inhibitors of constitutive and inducible cyclooxygenase. Proc Natl Acad Sci U S A. 1993 Dec 15;90(24):11693-7.|[2]Rosa AC, et al. Prevention of bleomycin-induced lung inflammation and fibrosis in mice by naproxen and JNJ7777120 treatment. J Pharmacol Exp Ther. 2014 Nov;351(2):308-16.|[3]Krekels EH, et al. Pharmacokinetic-pharmacodynamic modeling of the inhibitory effects of naproxen on the time-courses of inflammatory pain, fever, and the ex vivo synthesis of TXB2 and PGE2 in rats.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-15030AR/Naproxen-sodium-Standard-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-15030AR/
Clinical Information
Launched
CAS Number
26159-34-2
Available Sizes
Curated Selection
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