Human Acyl-CoA Thioesterase 11 (ACOT11)

<strong>Human Acyl-CoA Thioesterase 11 (ACOT11)</strong>_x000D_ <strong>Catalog number:</strong> B2015486_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 10 ug_x000D_ <strong>Molecular Weight or Concentration:</strong> 29.9 kDa (268 aa)_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20°C_x000D_ <strong>Keywords:</strong> Acyl-coenzyme A thioesterase 11, Acyl-CoA thioester hydrolase 11, Adipose-associated thioesterase, Brown fat-inducible thioesterase, BFIT, BFIT1, BFIT2, KIAA0707, THEA, ACO11_HUMAN, StAR related lipid transfer (START) domain containing 14, START domain containing 14, STARD14, Thioesterase adipose associated_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Kawaguchi K, Mukai E, Watanabe S, Yamashita A, Morita M, So T, Imanaka T. Acyl-CoA thioesterase activity of peroxisomal ABC protein ABCD1 is required for the transport of very long-chain acyl-CoA into peroxisomes Sci Rep. 2021 Jan 26;11(1):2192._x000D_ 2: Jung SH, Lee HC, Hwang HJ, Park HA, Moon YA, Kim BC, Lee HM, Kim KP, Kim YN, Lee BL, Lee JC, Ko YG, Park HJ, Lee JS. Acyl-CoA thioesterase 7 is involved in cell cycle progression via regulation of PKCζ-p53-p21 signaling pathway Cell Death Dis. 2017 May 18;8(5):e2793._x000D_ 3: Wang B, Zhang H, Chen YF, Hu LQ, Tian YY, Tong HW, Wang G, Chen C, Yuan P. Acyl-CoA thioesterase 9 promotes tumour growth and metastasis through reprogramming of fatty acid metabolism in hepatocellular carcinoma Liver Int. 2022 Nov;42(11):2548-2561._x000D_ 4: Hunt MC, Rautanen A, Westin MA, Svensson LT, Alexson SE. Analysis of the mouse and human acyl-CoA thioesterase (ACOT) gene clusters shows that convergent, functional evolution results in a reduced number of human peroxisomal ACOTs FASEB J. 2006 Sep;20(11):1855-64._x000D_ 5: Liu Y, Zeng L, Yang Y, Chen C, Wang D, Wang H. Acyl-CoA thioesterase 1 prevents cardiomyocytes from Doxorubicin-induced ferroptosis via shaping the lipid composition Cell Death Dis. 2020 Sep 15;11(9):756._x000D_ 6: Qu X, Allan A, Chui G, Hutchings TJ, Jiao P, Johnson L, Leung WY, Li PK, Steel GR, Thompson AS, Threadgill MD, Woodman TJ, Lloyd MD. Hydrolysis of ibuprofenoyl-CoA and other 2-APA-CoA esters by human acyl-CoA thioesterases-1 and -2 and their possible role in the chiral inversion of profens Biochem Pharmacol. 2013 Dec 1;86(11):1621-5._x000D_ 7: Kiema TR, Harijan RK, Strozyk M, Fukao T, Alexson SE, Wierenga RK. The crystal structure of human mitochondrial 3-ketoacyl-CoA thiolase (T1): insight into the reaction mechanism of its thiolase and thioesterase activities Acta Crystallogr D Biol Crystallogr. 2014 Dec 1;70(Pt 12):3212-25._x000D_ 8: Hussain SA, Garcia A, Khan MAK, Nosheen S, Zhang Y, Koffas MAG, Garre V, Lee SC, Song Y. Increased Accumulation of Medium-Chain Fatty Acids by Dynamic Degradation of Long-Chain Fatty Acids in Mucor circinelloides Genes (Basel). 2020 Aug 5;11(8):890._x000D_ 9: Jump DB, Botolin D, Wang Y, Xu J, Christian B, Demeure O. Fatty acid regulation of hepatic gene transcription J Nutr. 2005 Nov;135(11):2503-6._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/24284429">10: Mühlroth A, Li K, Røkke G, Winge P, Olsen Y, Hohmann-Marriott MF, Vadstein O, Bones AM. Pathways of lipid metabolism in marine algae, co-expression network, bottlenecks and candidate genes for enhanced production of EPA and DHA in species of Chromista Mar Drugs. 2013 Nov 22;11(11):4662-97. </a>_x000D_ _x000D_ <strong>Products Related to Human Acyl-CoA Thioesterase 11 (ACOT11) can be found at</strong> <a href="https://moleculardepot.com/product-category/Enzymes/"> Enzymes</a>