DS08701581
DS08701581 is an inhibitor of FER tyrosine kinase with IC50. DS08701581 has anti-tumor activity and oral activity[1].
Product Specifications
CAS Number
[3074776-78-3]
UNSPSC
12352005
Target
EGFR
Type
Reference compound
Related Pathways
JAK/STAT Signaling; Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ds08701581.html
Smiles
O=C1NN=CC2=C(C#N)C(N[C@H]3[C@@H](N)CCCC3)=NC(NC4=CC=CC(N5C[C@H](C)O[C@H](C)C5)=C4)=C21
Molecular Formula
C26H32N8O2
Molecular Weight
488.58
References & Citations
[1]Toru Taniguchi, et al. Optimization of Novel Pyrido-pyridazinone Derivatives as FER Tyrosine Kinase Inhibitors, Leading to the Potent DS08701581. ACS Med. Chem. Lett. 2024
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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