DS08701581

DS08701581 is an inhibitor of FER tyrosine kinase with IC50. DS08701581 has anti-tumor activity and oral activity[1].

Product Specifications

CAS Number

[3074776-78-3]

UNSPSC

12352005

Target

EGFR

Type

Reference compound

Related Pathways

JAK/STAT Signaling; Protein Tyrosine Kinase/RTK

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/ds08701581.html

Smiles

O=C1NN=CC2=C(C#N)C(N[C@H]3[C@@H](N)CCCC3)=NC(NC4=CC=CC(N5C[C@H](C)O[C@H](C)C5)=C4)=C21

Molecular Formula

C26H32N8O2

Molecular Weight

488.58

References & Citations

[1]Toru Taniguchi, et al. Optimization of Novel Pyrido-pyridazinone Derivatives as FER Tyrosine Kinase Inhibitors, Leading to the Potent DS08701581. ACS Med. Chem. Lett. 2024

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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