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HIF-2α-IN-11

HIF-2α-IN-11 (1) is a HIF-2α inhibitor, with an IC50 of 59.2 nM[1].

Product Specifications

CAS Number

[3034589-50-6]

UNSPSC

12352005

Target

HIF/HIF Prolyl-Hydroxylase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/hif-2α-in-11.html

Smiles

FC(F)(F)S(=O)(C1=C2C(C[C@H]([C@H]2O)F)=C([C@@H]3C4=C(F)C=C(F)C=C4CCCC3)C=C1)=O

Molecular Formula

C21H18F6O3S

Molecular Weight

464.42

References & Citations

[1]Wujie, et al. Benzo[7]annulene derivative, pharmaceutical composition comprising same, and medical uses thereof. Patent. WO2024067463A1.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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