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Obscurolide A1

Obscurolide A1 is a Phosphodiesterase (PDE) inhibitor (IC50=8 mM) that can be obtained from Streptomyces viridochromogenes culture. Obscurolide A1 has the potential to study neurological and inflammatory diseases[1].

Product Specifications

CAS Number

144397-99-9

UNSPSC

12352005

Hazard Statement

H302+H312+H332-H319

Target

Phosphodiesterase (PDE)

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/obscurolide-a1.html

Solubility

10 mM in DMSO

Smiles

O=C(C1=CC=C(C=C1)NC(C(O2)/C=C/C(C)O)CC2=O)O

Molecular Formula

C15H17NO5

Molecular Weight

291.30

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P501

References & Citations

[1]Hoff H, et al. Metabolic products of microorganisms. 261. Obscurolides, a novel class of phosphodiesterase inhibitors from streptomyces. I. Production, isolation, structural elucidation and biological activity of obscurolides A1 to A4. J Antibiot (Tokyo) . 1992 Jul;45 (7) :1096-107.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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