Boc-NH-O-C1-NHS ester

Boc-NH-O-C1-NHS ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Product Specifications

CAS Number

[80366-85-4]

UNSPSC

12352005

Hazard Statement

H315, H319, H335

Target

PROTAC Linkers

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/boc-nh-o-c1-nhs-ester.html

Purity

98.0

Solubility

DMSO : 250 mg/mL (ultrasonic)

Smiles

O=C1CCC(N1OC(CONC(OC(C)(C)C)=O)=O)=O

Molecular Formula

C11H16N2O7

Molecular Weight

288.25

Precautions

H315, H319, H335

References & Citations

[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Alkyl/ether Linkers

Available Sizes

Curated Selection

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