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AMG580

Product Specifications

UNSPSC Description

AMG580 is a selective PDE10A antagonist with subnanomolar affinity for rat, primate, and human PDE10A. AMG580 can be used for the research of noninvasive radiotracer[1].

Target Antigen

Phosphodiesterase (PDE)

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/amg580.html

Smiles

O=C(C1=NC2=C(N1)C=CC=C2)C3=CC=C(C=C3)OC4=NC=CN=C4C5CCN(CC5)C(C(C)F)=O

Molecular Weight

473.50

References & Citations

[1]Chen H, et al. AMG 580: a novel small molecule phosphodiesterase 10A (PDE10A) positron emission tomography tracer. J Pharmacol Exp Ther. 2015 Feb;352(2):327-37.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-124392/AMG580-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-124392/

Clinical Information

No Development Reported

CAS Number

1227067-71-1

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