S-Methoprene

S-Methoprene is an insect juvenile hormone analog and effective insecticide that blocks the transition from pupa to adult. S-Methoprene is also a CB (1) receptor ligand and inhibits the binding of the CB1 receptor antagonist [3H]CP-55940 to the CB1 receptor (IC50: 19.31 μM) [1][2].

Product Specifications

CAS Number

[65733-16-6]

Product Name Alternative

(+) -Methoprene; (7S) -Methoprene

UNSPSC

12352211

Hazard Statement

H315, H319, H335

Target

Cannabinoid Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/s-methoprene.html

Purity

98.58

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CC(C)(OC)CCC[C@H](C)C/C=C/C(C)=C/C(OC(C)C)=O

Molecular Formula

C19H34O3

Molecular Weight

310.47

Precautions

H315, H319, H335

References & Citations

[1]Adnan SM, et al. Accelerated Sexual Maturation in Methoprene-Treated Sterile and Fertile Male Queensland Fruit Flies (Diptera: Tephritidae), and Mosquito Larvicide as an Economical and Effective Source of Methoprene. J Econ Entomol. 2019 Dec 9;112 (6) :2842-2849.|[2]Dhopeshwarkar AS, et al. The actions of benzophenanthridine alkaloids, piperonyl butoxide and (S) -methoprene at the G-protein coupled cannabinoid CB₁ receptor in vitro. Eur J Pharmacol. 2011 Mar 1;654 (1) :26-32.