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Acacetin 7-O- (6-O-malonylglucoside)

Acacetin 7-O- (6-O-malonylglucoside) is a monoamine oxidase inhibitor with strong inhibitory effects on monoamine oxidase A (MAO-A) and monoamine oxidase B (MAO-B) with IC50 values ​​of 2.34 and 1.87 μM, respectively. Acacetin 7-O- (6-O-malonylglucoside) is a reversible MAO inhibitor that can be used in the research of neurodegenerative diseases and affective disorders[1].

Product Specifications

CAS Number

155049-92-6

UNSPSC

12352005

Target

Monoamine Oxidase

Type

Natural Products

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/acacetin-7-o-6-o-malonylglucoside.html

Smiles

O=C1C2=C(O)C=C(O[C@@H]3O[C@@H]([C@H]([C@@H]([C@H]3O)O)O)COC(CC(O)=O)=O)C=C2OC(C4=CC=C(C=C4)OC)=C1

Molecular Formula

C25H24O13

Molecular Weight

532.45

References & Citations

[1]Lee H W, et al. Potent inhibitions of monoamine oxidase A and B by acacetin and its 7-O- (6-O-malonylglucoside) derivative from Agastache rugosa[J]. International journal of biological macromolecules, 2017, 104: 547-553.

Shipping Conditions

Room temperature

Scientific Category

Natural Products

Clinical Information

No Development Reported

Isoform

MAO-A; MAO-B

Available Sizes

Frequently Asked Questions

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