NSC111552
NSC111552 is a potent SARS-CoV-2 NSP14 MTase inhibitor. NSC111552 inhibits the FL-NAH binding to the SARS-CoV-2 NSP14 MTase with an IC50 of 5.1 μM[1].
Product Specifications
CAS Number
40420-48-2
UNSPSC
12352005
Hazard Statement
H302-H312-H332
Target
SARS-CoV
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/nsc111552.html
Smiles
O=C(C)C1=C(O)C2=C(C=CC=C2)C(O)=C1
Molecular Formula
C12H10O3
Molecular Weight
202.21
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501
References & Citations
[1]Samrat SK, et al. A universal fluorescence polarization high throughput screening assay to target the SAM-binding sites of SARS-CoV-2 and other viral methyltransferases. Emerg Microbes Infect. 2023 Dec;12 (1) :2204164.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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