Human GPR75 Full Length Protein, Flag, His Tag (Detergent)
Human GPR75 Full Length Protein, Flag, His Tag (GP5-H52D3) is expressed from human 293 cells (HEK293) . It contains AA Met 1 - Val 540 (Accession # O95800) .
Product Specifications
Background
G protein-coupled receptor that is activated by the chemokine CCL5/RANTES. Probably coupled to heterotrimeric Gq proteins, it stimulates inositol trisphosphate production and calcium mobilization upon activation. Together with CCL5/RANTES, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. CCL5/RANTES may also regulate insulin secretion by pancreatic islet cells through activation of this receptor.
Specifications
This protein carries flag tag at the N-terminus and polyhistidine tag at the C-terminus. The protein has a calculated MW of 78.4 kDa.
Accession Number
O95800
Expression Region
Met 1 - Val 540
Host
HEK293
Target
GPR75
Conjugation
Unconjugated
Tag
N-Flag & C-10xHis
Source
Human
Stability
● The product MUST be stored at -70°C or lower upon receipt; ● -70°C for 3 months under sterile conditions.
Endotoxin
1.0 EU per μg
Purity
90%
Bioactivity
Immobilized Human GPR75 Full Length Protein, Flag,His Tag (Cat. No. GP5-H52D3) at 0.5 μg/mL (100 μL/well) can bind Anti-GPR75 antibody, Rabbit IgG with a linear range of 0.02-2.5 μg/mL (QC tested).
Format
Liquid
Buffer
50 mM HEPES, 150 mM NaCl, DDM, CHS, pH7.5
Additives
Glycerol
Molecular Weight
78.4 kDa
Shipping Conditions
Dry ice
Storage Conditions
-70°C
Package Size
500ug*1
Product Datasheet
Https://www.acrobiosystems.com/static/main/products/pdf/ds/GP5-H52D3.pdf
Species
Human
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