Inclisiran (sodium)
Inclisiran sodium is a double-stranded small interfering RNA (siRNA) molecule. Inclisiran sodium inhibits the transcription of PCSK9. Inclisiran sodium inhibits Pyroptosis, activates PPARγ, and reduces NLRP3, cleaved caspase-1, IL-1β, and IL-18. Inclisiran sodium has anti-inflammatory, lipid-regulating and anti-atherosclerotic activities. Inclisiran sodium can be used in researches of hyperlipidemia and cardiovascular disease (CVD) [1][2][3].
Product Specifications
Product Name Alternative
ALN-PCSsc (sodium)
UNSPSC
12352208
Target
Caspase; Interleukin Related; NOD-like Receptor (NLR) ; PCSK9; PPAR; Pyroptosis; Small Interfering RNA (siRNA)
Type
Oligonucleotides
Related Pathways
Apoptosis; Cell Cycle/DNA Damage; Epigenetics; Immunology/Inflammation; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Applications
Neuroscience-Neuromodulation
Field of Research
Metabolic Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/inclisiran-sodium.html
Purity
98.91
Solubility
10 mM in H2O
Smiles
[Inclisiran(sodium)]
Molecular Formula
C529H707F12N176O316P43S6.xNa
Molecular Weight
16339.6 (free acid)
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Oligonucleotides
Clinical Information
Launched
Isoform
Caspase 1; IL-1; NLRP3; PPARγ
Citation 01
Available Sizes
Frequently Asked Questions
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