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Human CD20 / MS4A1 Full Length Protein, Flag, His Tag (Detergent)

CD20 (gene: MS4A1), a member of the tetraspanin superfamily, has four transmembrane domains and the antibody-binding ECL2 loop; it is exclusively expressed in the B cell lineage (from late pro-B cells to mature B cells) (downregulated or absent in plasma cells) and regulates B cell development, activation, and survival by modulating BCR-mediated calcium signaling and downstream pathways.

Product Specifications

Background

CD20 (gene: MS4A1), a member of the tetraspanin superfamily, has four transmembrane domains and the antibody-binding ECL2 loop; it is exclusively expressed in the B cell lineage (from late pro-B cells to mature B cells) (downregulated or absent in plasma cells) and regulates B cell development, activation, and survival by modulating BCR-mediated calcium signaling and downstream pathways.

Specifications

This protein carries a Flag tag at the N-terminus and polyhistidine tag at the C-terminus. The protein has a calculated MW of 37.3 kDa. The protein migrates as 40-43 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

Accession Number

P11836-1

Expression Region

Met 1 - Pro 297

Host

HEK293

Target

CD20

Conjugation

Unconjugated

Tag

N-Flag & C-12xHis

Stability

The product MUST be stored at -70°C or lower upon receipt; -70°C for 12 months under sterile conditions.

Endotoxin

1.0 EU per μg

Purity

90%

Format

Liquid

Buffer

50 mM HEPES, 150 mM NaCl, DDM, CHS, pH7.5

Additives

Glycerol

Molecular Weight

37.3 kDa

Additionnal Information

Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments

Shipping Conditions

Dry ice

Storage Conditions

-70°C

Package Size

20ug*1

Host or Source

HEK293

Species

Human

Protein ID

P11836-1

Preservative

Glycerol

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