ZPCK
ZPCK is an oral active proagent of gemcitabine that was designed for improved oral bioavailability[1].
Product Specifications
CAS Number
[26049-94-5]
Product Name Alternative
SL-01
UNSPSC
12352005
Hazard Statement
H314
Target
Apoptosis; Autophagy; DNA/RNA Synthesis; Nucleoside Antimetabolite/Analog
Type
Reference compound
Related Pathways
Apoptosis; Autophagy; Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/zpck.html
Purity
99.0
Solubility
DMSO : 33 mg/mL (ultrasonic; warming)
Smiles
O=C(OCC1=CC=CC=C1)N[C@@H](CC2=CC=CC=C2)C(CCl)=O
Molecular Formula
C18H18ClNO3
Molecular Weight
331.79
Precautions
H314
References & Citations
[1]Zhao C, et al. Pharmacokinetics and metabolism of SL-01, a prodrug of gemcitabine, in rats. Cancer Chemother Pharmacol. 2013 Jun;71 (6) :1541-50.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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